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cardiac electrocardiograms ecg  (ADInstruments)


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    Structured Review

    ADInstruments cardiac electrocardiograms ecg
    (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with control or 10 mM NAM-supplemented buffer. <t>Electrocardiogram</t> <t>(ECG)</t> was recorded with the positive electrode (‘+’) positioned beneath the apex of the left ventricle, and the negative (‘-’) and ground (‘0’) electrodes on the cannula. Programmed electrical stimulation was applied via a pacing electrode (‘P’) placed on the surface of the right atrium. (B) Representative <t>ECG</t> traces from AF-negative (top) and AF-positive (bottom) mouse hearts. (C-E) AF incidence, episode count and burden in hearts from the control (n=6 for both sexes) and 10 mM NAM (n=5 for both sexes). Data are expressed as mean ± standard error of the mean. Chi-square test was used for AF incidence and Scheirer-Ray-Hare test followed by Dunn’s post-hoc test was used for AF episode count and burden.
    Cardiac Electrocardiograms Ecg, supplied by ADInstruments, used in various techniques. Bioz Stars score: 96/100, based on 214 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cardiac electrocardiograms ecg/product/ADInstruments
    Average 96 stars, based on 214 article reviews
    cardiac electrocardiograms ecg - by Bioz Stars, 2026-04
    96/100 stars

    Images

    1) Product Images from "Dual effects of nicotinamide on aging-related arrhythmia: protective at low dose, proarrhythmic at high doses"

    Article Title: Dual effects of nicotinamide on aging-related arrhythmia: protective at low dose, proarrhythmic at high doses

    Journal: bioRxiv

    doi: 10.1101/2025.09.22.677785

    (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with control or 10 mM NAM-supplemented buffer. Electrocardiogram (ECG) was recorded with the positive electrode (‘+’) positioned beneath the apex of the left ventricle, and the negative (‘-’) and ground (‘0’) electrodes on the cannula. Programmed electrical stimulation was applied via a pacing electrode (‘P’) placed on the surface of the right atrium. (B) Representative ECG traces from AF-negative (top) and AF-positive (bottom) mouse hearts. (C-E) AF incidence, episode count and burden in hearts from the control (n=6 for both sexes) and 10 mM NAM (n=5 for both sexes). Data are expressed as mean ± standard error of the mean. Chi-square test was used for AF incidence and Scheirer-Ray-Hare test followed by Dunn’s post-hoc test was used for AF episode count and burden.
    Figure Legend Snippet: (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with control or 10 mM NAM-supplemented buffer. Electrocardiogram (ECG) was recorded with the positive electrode (‘+’) positioned beneath the apex of the left ventricle, and the negative (‘-’) and ground (‘0’) electrodes on the cannula. Programmed electrical stimulation was applied via a pacing electrode (‘P’) placed on the surface of the right atrium. (B) Representative ECG traces from AF-negative (top) and AF-positive (bottom) mouse hearts. (C-E) AF incidence, episode count and burden in hearts from the control (n=6 for both sexes) and 10 mM NAM (n=5 for both sexes). Data are expressed as mean ± standard error of the mean. Chi-square test was used for AF incidence and Scheirer-Ray-Hare test followed by Dunn’s post-hoc test was used for AF episode count and burden.

    Techniques Used: Ex Vivo, Control

    (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with 0 mM NAM (control) or 100 mM NAM-supplemented buffer. (B) Representative electrocardiogram (ECG) shows that acute perfusion with 100 mM NAM rapidly induced VF, contractile dysfunction, and eventually led to cardiac arrest (n=4 males, 2 females). (C) Representiative blots and (D) quantification of acetylated SERCA2a levels of left venticular tissue from control and 100 mM NAM-perfused ex vivo mouse hearts (n=3). Data are expressed as mean ± standard error of the mean. Two tailed unpaired Student t-test was used.
    Figure Legend Snippet: (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with 0 mM NAM (control) or 100 mM NAM-supplemented buffer. (B) Representative electrocardiogram (ECG) shows that acute perfusion with 100 mM NAM rapidly induced VF, contractile dysfunction, and eventually led to cardiac arrest (n=4 males, 2 females). (C) Representiative blots and (D) quantification of acetylated SERCA2a levels of left venticular tissue from control and 100 mM NAM-perfused ex vivo mouse hearts (n=3). Data are expressed as mean ± standard error of the mean. Two tailed unpaired Student t-test was used.

    Techniques Used: Ex Vivo, Control, Two Tailed Test



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    (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with control or 10 mM NAM-supplemented buffer. Electrocardiogram (ECG) was recorded with the positive electrode (‘+’) positioned beneath the apex of the left ventricle, and the negative (‘-’) and ground (‘0’) electrodes on the cannula. Programmed electrical stimulation was applied via a pacing electrode (‘P’) placed on the surface of the right atrium. (B) Representative ECG traces from AF-negative (top) and AF-positive (bottom) mouse hearts. (C-E) AF incidence, episode count and burden in hearts from the control (n=6 for both sexes) and 10 mM NAM (n=5 for both sexes). Data are expressed as mean ± standard error of the mean. Chi-square test was used for AF incidence and Scheirer-Ray-Hare test followed by Dunn’s post-hoc test was used for AF episode count and burden.

    Journal: bioRxiv

    Article Title: Dual effects of nicotinamide on aging-related arrhythmia: protective at low dose, proarrhythmic at high doses

    doi: 10.1101/2025.09.22.677785

    Figure Lengend Snippet: (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with control or 10 mM NAM-supplemented buffer. Electrocardiogram (ECG) was recorded with the positive electrode (‘+’) positioned beneath the apex of the left ventricle, and the negative (‘-’) and ground (‘0’) electrodes on the cannula. Programmed electrical stimulation was applied via a pacing electrode (‘P’) placed on the surface of the right atrium. (B) Representative ECG traces from AF-negative (top) and AF-positive (bottom) mouse hearts. (C-E) AF incidence, episode count and burden in hearts from the control (n=6 for both sexes) and 10 mM NAM (n=5 for both sexes). Data are expressed as mean ± standard error of the mean. Chi-square test was used for AF incidence and Scheirer-Ray-Hare test followed by Dunn’s post-hoc test was used for AF episode count and burden.

    Article Snippet: Cardiac electrocardiograms (ECG) were recorded using three electrodes (MLA1213 and MLA1212, ADInstruments).

    Techniques: Ex Vivo, Control

    (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with 0 mM NAM (control) or 100 mM NAM-supplemented buffer. (B) Representative electrocardiogram (ECG) shows that acute perfusion with 100 mM NAM rapidly induced VF, contractile dysfunction, and eventually led to cardiac arrest (n=4 males, 2 females). (C) Representiative blots and (D) quantification of acetylated SERCA2a levels of left venticular tissue from control and 100 mM NAM-perfused ex vivo mouse hearts (n=3). Data are expressed as mean ± standard error of the mean. Two tailed unpaired Student t-test was used.

    Journal: bioRxiv

    Article Title: Dual effects of nicotinamide on aging-related arrhythmia: protective at low dose, proarrhythmic at high doses

    doi: 10.1101/2025.09.22.677785

    Figure Lengend Snippet: (A) Experimental scheme of Langendorff ex vivo mouse hearts perfused with 0 mM NAM (control) or 100 mM NAM-supplemented buffer. (B) Representative electrocardiogram (ECG) shows that acute perfusion with 100 mM NAM rapidly induced VF, contractile dysfunction, and eventually led to cardiac arrest (n=4 males, 2 females). (C) Representiative blots and (D) quantification of acetylated SERCA2a levels of left venticular tissue from control and 100 mM NAM-perfused ex vivo mouse hearts (n=3). Data are expressed as mean ± standard error of the mean. Two tailed unpaired Student t-test was used.

    Article Snippet: Cardiac electrocardiograms (ECG) were recorded using three electrodes (MLA1213 and MLA1212, ADInstruments).

    Techniques: Ex Vivo, Control, Two Tailed Test